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LAB MEMBERS
Principal Investigator
Jeffrey MacKeigan, Ph.D., is a senior advisor for Michigan State University Office of Research and Innovation. He also serves as a senior fellow for research infrastructure in the Office of Research and Innovation, and professor in the Department of Pediatrics and Human Development in the MSU College of Human Medicine.
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Dr. MacKeigan’s research uses a variety of cutting-edge technologies, combined with tumor cell biology and drug discovery expertise to study complex diseases. The MacKeigan laboratory has been awarded over 35 externally funded research grants, many from the National Institutes of Health, including the National Cancer Institute.
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Prior to becoming a senior advisor, MacKeigan was assistant dean for research in the MSU College of Human Medicine. Before joining MSU, MacKeigan held positions at the Novartis Institutes for Biomedical Research and Van Andel Research Institute.
Dr. MacKeigan has fostered several important relationships for the university with leaders and researchers at hospital systems, universities, and biomedical research institutes and with the many great collaborators in the region. His additional leadership roles include serving as co-chair of the MSU Health Sciences Council, and as a board member of the American Cancer Society in Michigan.
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MacKeigan holds a bachelor’s degree in molecular, cellular, and developmental biology from the University of Colorado and earned a Ph.D. in microbiology and immunology from the University of North Carolina Medical School at the Lineberger Comprehensive Cancer Center. He completed his post-doctoral training at Harvard Medical School with fellowship funding from the American Cancer Society.
Assistant Professor
Katie received a B.S. in biology from Grand Valley State University in 2006. She attended graduate school at Michigan State University where she earned her Ph.D. in cell and molecular biology. During her doctoral studies, Katie focused on PI(3)P signaling and autophagy using RNAi, in silico virtual library screening, and mathematical modeling. Katie has been a scientific project leader in the MacKeigan Lab since 2011, where she helps guide and implement the lab’s research strategy. Katie has a significant role in laboratory training, grant writing, and manuscript development.
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Research Associate
Stephanie earned a B.A. in chemistry from Hope College in 2009, and received her M.S. in cell and molecular biology, biotechnology, PSM from Grand Valley State University. While completing her M.S. in 2013, she became a research technologist at Michigan State University in the Paumier Lab, where she studied neuroprotective therapeutics in a novel model of alpha-synucleinopathy. In 2015, she joined the MacKeigan Laboratory as a research associate and focuses on therapeutic targets of autophagy in non-small cell lung cancer.
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Endowed Director, Haworth Innovative Therapeutics Clinic
Dr. David Hoogstra completed his B.A. at Calvin College in Grand Rapids, Michigan. He obtained his M.D. from Wayne State University School of Medicine in 2016. While at Wayne State, Dr. Hoogstra received several awards, including recognition for distinction in biomedical research. After receiving his M.D., he began his pediatric residency at Helen DeVos Children’s Hospital in pediatric hematology and oncology. Dr. Hoogstra’s research aims to determine the therapeutic potential of combining autophagy inhibition with ALK inhibition and exploring novel radiopharmaceuticals in pediatric cancer.
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Dr. Hoogstra is the Endowed Director, Haworth Innovative Therapeutics Clinic in the Pediatric Hematology/Oncology Division at Helen DeVos Children’s Hospital at Corewell Health and Assistant Professor, Michigan State University College of Human Medicine
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